How are paracetamol and ibuprofen different?
Paracetamol (the active ingredient in Panadol) relieves pain and reduces fever but has little effect on inflammation. Ibuprofen (in Brufen) is a non-steroidal anti-inflammatory drug (NSAID) — it also reduces pain and fever and tackles inflammation and swelling.
Quick comparison
| Paracetamol (Panadol) | Ibuprofen (Brufen) | |
|---|---|---|
| Best for | Fever, headache, general pain | Pain with swelling, period pain, back/muscle pain |
| Anti-inflammatory | No | Yes |
| Stomach | Gentle | Take with food; can irritate |
| Usual adult dose | 500 mg–1 g every 4–6 h (max 8 tablets/day) | 400 mg up to 3 times a day with food |
| Avoid if | Liver disease (get advice) | Stomach ulcers, severe heart failure, late pregnancy |
Which should I take for a fever?
Paracetamol is usually the first choice for fever because it is effective and gentle on the stomach. Ibuprofen also lowers fever and can help if there is associated aching or inflammation.
Can I take paracetamol and ibuprofen together?
Yes. Because they work differently, they can be taken at the same time or alternated for stronger relief. Keep to the dose on each pack and do not exceed the daily maximum for either. If you are unsure, ask a pharmacist.
Important safety points
- Never take two products that both contain paracetamol at the same time (overdose risk).
- Take ibuprofen with or after food to protect your stomach.
- For children, use the syrup formulation and dose by age/weight.
- See a doctor if fever lasts more than 3 days or pain is severe or worsening.